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Microparticle Phosphatidylserine Mediates Coagulation: Involvement in Tumor Progression and Metastasis

24 Mar 2023

Abstract excerpt

Tumor progression and cancer metastasis has been linked to the release of microparticles (MPs), which are shed upon cell activation or apoptosis and display parental cell antigens, phospholipids such as phosphatidylserine (PS), and nucleic acids on their external surfaces. In this review, we highlight the biogenesis of MPs as well as the pathophysiological processes of PS externalization and its involvement in...

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PMID: 37046617
DOI: 10.3390/cancers15071957

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