Article
In vitro and ex vivo activation of the TLR5 signaling pathway in intestinal epithelial cells by a commensal Escherichia coli strain.
The Journal of biological chemistry - 8 Oct 2004
Bambou Jean-Christophe, Giraud Antoine, Menard Sandrine, Begue Bernadette, Rakotobe Sabine, Heyman Martine, Taddei François, Cerf-Bensussan Nadine, Gaboriau-Routhiau Valérie
Abstract excerpt
The capacity of non-pathogenic enteric bacteria to induce a pro-inflammatory response is under debate in terms of its effect on the symbiosis between the mammalian host and its commensal gut microflora. Activation of NF-kappaB and induction of interleukin-8 (IL-8) and CCL-20 by the commensal Escherichia coli strain MG1655 were first studied in vitro in the human intestinal epithelial cell (IECs) lines HT29-19A...
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