Article
Mucosal interplay among commensal and pathogenic bacteria: Lessons from flagellin and Toll‐like receptor 5
21 Apr 2006
Abstract excerpt
Toll-like receptors (TLR) detect pathogen-associated molecular patterns (PAMP) and play a crucial role in triggering immunity. Due to their large surfaces in direct contact with the environment, mucosal tissues are the major sites of PAMP-TLR signalling. How innate and adaptive immunity are triggered through flagellin-TLR5 interaction is the main focus of the review. In view of recent reports on genetic...
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