Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Assessment of cytology based molecular analysis to guide targeted therapy in advanced non-small-cell lung cancer.

Oncotarget - 16 Feb 2016

Li Wenbin, Zhang Zhihui, Guo Lei, Qiu Tian, Ling Yun, Cao Jian, Guo Huiqin, Zhao Huan, Li Lin, Ying Jianming

Abstract excerpt

To investigate the use of molecular testing on cytological specimens in selecting advanced non-small cell lung cancer (NSCLC) patients who are adequate for targeted treatment, a total of 137 NSCLC cases were analyzed by fluorescence in situ hybridization (FISH) for anaplastic lymphoma kinase (ALK) rearrangements, and Epidermal growth factor receptor (EGFR), kirsten rat sarcoma viral oncogene homolog (KRAS)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anaplastic Lymphoma Kinase
Share to Biopsy, Fine-Needle

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carcinoma, Adenosquamous

Share to Cytodiagnosis

Share to Gene Rearrangement

Share to Molecular Targeted Therapy

Share to Receptor Protein-Tyrosine Kinases

Share to Survival Rate

Source

Open in PubMed Open full text

Identifiers

PMID: 26789109
DOI: 10.18632/oncotarget.6671
PMCID: PMC4884996

Genes

ALK
EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assessment of cytology based molecular analysis to guide targeted therapy in advanced non-small-cell lung cancer.PMID 26789109Read ↗

Role of Fluorescence in situ Hybridization in Lung Cancer CytologySemantic proximity Read ↗

Cytology samples and molecular biomarker testing in lung cancer-advantages and challenges.Semantic proximity Read ↗

Liquid-based cytology specimens for next-generation sequencing in lung adenocarcinoma: challenges and evaluation of targeted therapy.Semantic proximity Read ↗

Comprehensive epidermal growth factor receptor gene analysis from cytological specimens of non-small-cell lung cancers.Semantic proximity Read ↗

Suitability of thoracic cytology for new therapeutic paradigms in non-small cell lung carcinoma: high accuracy of tumor subtyping and feasibility of EGFR and KRAS molecular testing.Semantic proximity Read ↗

Diagnostic algorithm for detection of targetable driver mutations in lung adenocarcinomas: Comprehensive analyses of 205 cases with immunohistochemistry, real-time PCR and fluorescence in situ hybridization methods.Semantic proximity Read ↗

Detection of epidermal growth factor receptor mutation in non-small-cell lung carcinoma using cytological and histological specimens.Semantic proximity Read ↗

Anaplastic lymphoma kinase gene rearrangements in cytological samples of non-small cell lung cancer: comparison with histological assessment.Semantic proximity Read ↗

Feasibility of EBUS-TBNA for histopathological and molecular diagnostics of NSCLC-A retrospective single-center experience.Semantic proximity Read ↗

An evaluation study of EGFR mutation tests utilized for non-small-cell lung cancer in the diagnostic setting.Semantic proximity Read ↗

Identification of EGFR mutation, KRAS mutation, and ALK gene rearrangement in cytological specimens of primary and metastatic lung adenocarcinoma.Semantic proximity Read ↗

Cytology smears as excellent starting material for next-generation sequencing-based molecular testing of patients with adenocarcinoma of the lung.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.