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Article

Liquid-based cytology specimens for next-generation sequencing in lung adenocarcinoma: challenges and evaluation of targeted therapy.

BMC cancer - 20 Jun 2024

Xiao Xiaoyue, Sun ZiHan, Liang Shuo, Li Weihua, Guo HuiQin, Zhao Huan, Zhao LinLin, Ma HaiYue, Sun Yue, Wang Cong, Chang XinXiang, Zhang ZhiHui

Abstract excerpt

BACKGROUND: To explore challenges of liquid-based cytology (LBC) specimens for next-generation sequencing (NGS) in lung adenocarcinoma and evaluate the efficacy of targeted therapy. METHODS: A retrospective analysis was conducted on the NGS test of 357 cases of advanced lung adenocarcinoma LBC specimens and compared with results of histological specimens to assess the consistency. The impact of tumor cellularity...

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Identifiers

PMID: 38902688
DOI: 10.1186/s12885-024-12520-2
PMCID: PMC11188509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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