Article
Analysis of functional polymorphisms in apoptosis-related genes in primary open angle glaucoma.
Molecular vision - 1 Jan 2015
Lindner Ewald, Glatz Wilfried, Schwab Christoph, El-Shabrawi Yosuf, Mossböck Georg
Abstract excerpt
PURPOSE: Glaucoma is a disease with high heritability in which the degradation of retinal ganglion cells occurs via apoptosis. Therefore, we investigated the role of four functional apoptosis-related gene variants (Akt1 rs1130233, Bax rs4645878, Fas rs223476, and FasL rs763110) in patients with primary open angle glaucoma. METHODS: 334 patients with primary open angle glaucoma and 334 controls were recruited for...
Read the complete abstract on PubMed