Article
Association of TNFA -308 G/A and TNFRI +36 A/G gene polymorphisms with glaucoma.
Ophthalmic research - 1 Jan 2009
Razeghinejad Mohammad Reza, Rahat Feisal, Kamali-Sarvestani Eskandar
Abstract excerpt
OBJECTIVE: TNF-alpha is one of the most important factors recognized in the pathogenesis of open-angle glaucoma. Therefore, the association of single nucleotide polymorphisms in the TNFRI gene and the promoter region of the TNFA gene with glaucoma susceptibility was investigated in the present study. METHOD: In total, 223 patients with glaucoma and 202 unrelated controls were genotyped by allele-specific...
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