Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Primary open angle glaucoma in a Caucasian population is associated with the p53 codon 72 polymorphism.

Molecular vision - 22 Sept 2009

Daugherty Christopher L, Curtis Hilda, Realini Tony, Charlton Judie F, Zareparsi Sepideh

Abstract excerpt

PURPOSE: Apoptosis has been implicated as the mechanism for retinal ganglion cell death in primary open-angle glaucoma (POAG), a complex neurodegenerative disease. There have been inconsistent reports regarding increased risk of POAG and a polymorphism (Arg72Pro) within the tumor suppressor gene,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Glaucoma, Open-Angle

Share to Tumor Suppressor Protein p53

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 19784392
PMCID: PMC2751801

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19784392-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Primary open angle glaucoma in a Caucasian population is associated with the p53 codon 72 polymorphism.PMID 19784392Read ↗

The p53 codon 72 PRO/PRO genotype may be associated with initial central visual field defects in caucasians with primary open angle glaucoma.Semantic proximity Read ↗

TP53 codon 72 polymorphism and the risk of glaucoma in a north Indian cohort: A genetic association study.Semantic proximity Read ↗

Distributions of p53 codon 72 polymorphism in primary open angle glaucomaSemantic proximity Read ↗

Association between p53 codon 72 (Arg72Pro) polymorphism and primary open-angle glaucoma in Iranian patients.Semantic proximity Read ↗

Association between the p53 codon 72 polymorphism and primary open-angle glaucoma risk: Meta-analysis based on 11 case-control studies.Semantic proximity Read ↗

A polymorphism at codon 31 of gene p21 is not associated with primary open angle glaucoma in Caucasians.Semantic proximity Read ↗

The relationship of TP53 and GRIN2B gene polymorphisms with risk of occurrence and progression of primary open-angle glaucoma in a Polish population.Semantic proximity Read ↗

Analysis of functional polymorphisms in apoptosis-related genes in primary open angle glaucoma.Semantic proximity Read ↗

Association of polymorphisms of tumor necrosis factor and tumor protein p53 with primary open-angle glaucoma.Semantic proximity Read ↗

Identification of TP53BP2 as a Novel Candidate Gene for Primary Open Angle Glaucoma by Whole Exome Sequencing in a Large Multiplex Family.Semantic proximity Read ↗

Polymorphisms in OPA1 are associated with normal tension glaucoma.Semantic proximity Read ↗

The p53 codon 72 polymorphism (rs1042522) is associated with proliferative vitreoretinopathy: the Retina 4 Project.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.