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Article

Association of autophagy-related IRGM polymorphisms with latent versus active tuberculosis infection in a Chinese population.

Tuberculosis (Edinburgh, Scotland) - 1 Mar 2016

Lu Yanjun, Li Qian, Peng Jing, Zhu Yaowu, Wang Feng, Wang Chunyu, Wang Xiong

Abstract excerpt

The autophagy-related immunity-related GTPase family M protein, IRGM, plays an important role in the defense against tuberculosis (TB) infection. IRGM polymorphisms are associated with TB infection susceptibility, and recent studies demonstrate host genetic differences between active and latent TB. Here, we investigated the association between IRGM polymorphisms and TB infection type in a Chinese population. We...

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Autophagy
Bacteriological Techniques
GTP-Binding Proteins
Host-Pathogen Interactions
Latent Tuberculosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Diagnostic Techniques

Protective Factors

Tuberculosis, Pulmonary

Source

Identifiers

PMID: 26980495
DOI: 10.1016/j.tube.2016.01.001

Genes

IRGM

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