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Article

Identification of a novel IRGM promoter single nucleotide polymorphism associated with tuberculosis.

Clinica chimica acta; international journal of clinical chemistry - 11 Nov 2010

Che Nanying, Li Song, Gao Tiejie, Zhang Zhiguo, Han Yuefei, Zhang Xuxia, Sun Yong, Liu Yi, Sun Zhaogang, Zhang Jianyuan, Ren Weicong, Tian Miao, Li Yan, Li Wensheng, Cheng Jun, Li Chuanyou

Abstract excerpt

BACKGROUND: Human immunity-related GTPase M (IRGM) is found to play an important role in defense against intracellular pathogen Mycobacterium tuberculosis in vitro by regulating autophagy. To verify whether single nucleotide polymorphisms (SNPs) in the promoter region of IRGM gene are associated...

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Source

Identifiers

PMID: 20547146
DOI: 10.1016/j.cca.2010.06.009

Genes

IRGM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20547146-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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