Impact of IRGM gene promoter polymorphisms on susceptibility to chronic HBV infection.

doi:10.1111/iji.12661

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Impact of IRGM gene promoter polymorphisms on susceptibility to chronic HBV infection.

International journal of immunogenetics - 1 Jun 2024

Cheng Hai, Ouyang Yaoling, Li Chengbin

Abstract excerpt

The autophagy gene immunity-related GTPase M (IRGM) can affect the immune response against intracellular pathogens. The study was performed to determine any possible association between three IRGM single-nucleotide polymorphisms (SNPs) (rs4958842, rs4958843 and rs4958846) and chronic hepatitis B virus (HBV) infection. A total of 171 chronic HBV-infected individuals and 171 healthy controls were collected....

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Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Promoter Regions, Genetic

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PMID: 38514898
DOI: 10.1111/iji.12661

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