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Article

Association of IRGM polymorphisms and susceptibility to pulmonary tuberculosis in Zahedan, Southeast Iran.

TheScientificWorldJournal - 1 Jan 2012

Bahari Gholamreza, Hashemi Mohammad, Taheri Mohsen, Naderi Mohammad, Eskandari-Nasab Ebrahim, Atabaki Mahdi

Abstract excerpt

Tuberculosis (TB) is a major cause of morbidity and mortality worldwide. IRGM1 is an important protein in the innate immune response against intracellular pathogens by regulating autophagy. Polymorphisms in the IRGM genes are known to influence expression levels and may be associated with outcome of infections. This case-control study was done on 150 patients with PTB and 150 healthy subjects to determine whether...

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Source

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Identifiers

PMID: 23049477
DOI: 10.1100/2012/950801
PMCID: PMC3461614

Genes

IRGM

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