Article
Genetic polymorphisms of IFNG and IFNGR1 in association with the risk of pulmonary tuberculosis.
Gene - 10 Jun 2014
Lü Jieqiong, Pan Hongqiu, Chen Yongzhong, Tang Shaowen, Feng Yan, Qiu Sangsang, Zhang Siming, Wu Liang, Xu Ruobing, Peng Xianzhen, Wang Jianming, Lu Cheng
Abstract excerpt
OBJECTIVE: Genetic host factors play an important role in controlling individual's susceptibility to the pathogen. This study aims to explore the single and joint effect of genetic polymorphisms of interferon-gamma (IFNG) and its receptor (IFNGR1) in association with the pulmonary tuberculosis in a Chinese Han population. METHODS: This population-based case control study consisted of 1434 pulmonary tuberculosis...
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