Article
An Analog-sensitive Version of the Protein Kinase Slt2 Allows Identification of Novel Targets of the Yeast Cell Wall Integrity Pathway.
The Journal of biological chemistry - 11 Mar 2016
Alonso-Rodríguez Esmeralda, Fernández-Piñar Pablo, Sacristán-Reviriego Almudena, Molina María, Martín Humberto
Abstract excerpt
The yeast cell wall integrity MAPK Slt2 mediates the transcriptional response to cell wall alterations through phosphorylation of transcription factors Rlm1 and SBF. However, the variety of cellular functions regulated by Slt2 suggests the existence of a significant number of still unknown substrates for this kinase. To identify novel Slt2 targets, we generated and characterized an analog-sensitive mutant of Slt2...
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