Article
Regulatory mechanisms for modulation of signaling through the cell integrity Slt2-mediated pathway in Saccharomyces cerevisiae.
The Journal of biological chemistry - 14 Jan 2000
Martín H, Rodríguez-Pachón J M, Ruiz C, Nombela C, Molina M
Abstract excerpt
Signal transduction mediated by the mitogen-activated protein kinase (MAPK) Slt2 pathway is essential to maintain the cell wall integrity in Saccharomyces cerevisiae. Stimulation of MAPK pathways results in activation by phosphorylation of conserved threonine and tyrosine residues of MAPKs. We have used an antibody that specifically recognizes dually phosphorylated Slt2 to gain insight into the activation and...
Topics
- DNA-Binding Proteins
- Fungal Proteins
- GTPase-Activating Proteins
- Genotype
- MAP Kinase Kinase 1
- MAP Kinase Kinase 2
- Mitogen-Activated Protein Kinase 1
- Mitogen-Activated Protein Kinase 3
- Mitogen-Activated Protein Kinase Kinases
- Mitogen-Activated Protein Kinases
- Phosphorylation
- Protein Serine-Threonine Kinases