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Article

Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast.

Molecular biology of the cell - 1 Nov 2008

Mousley Carl J, Tyeryar Kimberly, Ile Kristina E, Schaaf Gabriel, Brost Renee L, Boone Charles, Guan Xueli, Wenk Markus R, Bankaitis Vytas A

Abstract excerpt

Synthetic genetic array analyses identify powerful genetic interactions between a thermosensitive allele (sec14-1(ts)) of the structural gene for the major yeast phosphatidylinositol transfer protein (SEC14) and a structural gene deletion allele (tlg2Delta) for the Tlg2 target membrane-soluble N-ethylmaleimide-sensitive factor attachment protein receptor. The data further demonstrate Sec14 is required for proper...

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Identifiers

PMID: 18753406
DOI: 10.1091/mbc.e08-04-0426
PMCID: PMC2575146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast.PMID 18753406Read ↗

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An inducible ER-Golgi tether facilitates ceramide transport to alleviate lipotoxicity.Semantic proximity Read ↗

The clathrin adaptor Gga2p is a phosphatidylinositol 4-phosphate effector at the Golgi exit.Semantic proximity Read ↗

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