Article
Regulation of stress response signaling by the N-terminal dishevelled/EGL-10/pleckstrin domain of Sst2, a regulator of G protein signaling in Saccharomyces cerevisiae.
The Journal of biological chemistry - 21 Jun 2002
Burchett Scott A, Flanary Paul, Aston Christopher, Jiang Lixin, Young Kathleen H, Uetz Peter, Fields Stanley, Dohlman Henrik G
Abstract excerpt
All members of the regulator of G protein signaling (RGS) family contain a conserved core domain that can accelerate G protein GTPase activity. The RGS in yeast, Sst2, can inhibit a G protein signal leading to mating. In addition, some RGS proteins contain an N-terminal domain of unknown function. Here we use complementary whole genome analysis methods to investigate the function of the N-terminal Sst2 domain. To...
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