Article
Mitochondrial DNA variation and HIV-associated sensory neuropathy in CHARTER.
Journal of neurovirology - 1 Dec 2012
Holzinger Emily R, Hulgan Todd, Ellis Ronald J, Samuels David C, Ritchie Marylyn D, Haas David W, Kallianpur Asha R, Bloss Cinnamon S, Clifford David B, Collier Ann C, Gelman Benjamin B, Marra Christina M, McArthur Justin C, McCutchan J Allen, Morgello Susan, Simpson David M, Franklin Donald R, Rosario Debralee, Selph Doug, Letendre Scott, Grant Igor
Abstract excerpt
HIV-associated sensory neuropathy remains an important complication of combination antiretroviral therapy and HIV infection. Mitochondrial DNA haplogroups and single nucleotide polymorphisms (SNPs) have previously been associated with symptomatic neuropathy in clinical trial participants. We examined associations between mitochondrial DNA variation and HIV-associated sensory neuropathy in CNS HIV Antiretroviral...
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