The Barrett-associated variants at GDF7 and TBX5 also increase esophageal adenocarcinoma risk.

doi:10.1002/cam4.641

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The Barrett-associated variants at GDF7 and TBX5 also increase esophageal adenocarcinoma risk.

Cancer medicine - 1 May 2016

Becker Jessica, May Andrea, Gerges Christian, Anders Mario, Schmidt Claudia, Veits Lothar, Noder Tania, Mayershofer Rupert, Kreuser Nicole, Manner Hendrik, Venerito Marino, Hofer Jan-Hinnerk, Lyros Orestis, Ahlbrand Constantin J, Arras Michael, Hofer Sebastian, Heinrichs Sophie K M, Weise Katharina, Hess Timo, Böhmer Anne C, Kosiol Nils, Kiesslich Ralf, Izbicki Jakob R, Hölscher Arnulf H, Bollschweiler Elfriede, Malfertheiner Peter, Lang Hauke, Moehler Markus, Lorenz Dietmar, Ott Katja, Schmidt Thomas, Nöthen Markus M, Hackelsberger Andreas, Schumacher Brigitte, Pech Oliver, Vashist Yogesh, Vieth Michael, Weismüller Josef, Knapp Michael, Neuhaus Horst, Rösch Thomas, Ell Christian, Gockel Ines, Schumacher Johannes

Abstract excerpt

Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC) represent two stages within the esophagitis-metaplasia-dysplasia-adenocarcinoma sequence. Previously genetic risk factors have been identified that confer risk to BE and EAC development. However, to which extent the genetic variants confer risk to different stages of the BE/EAC sequence remains mainly unknown. In this study we analyzed three most...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adenocarcinoma

Share to Barrett Esophagus

Share to Bone Morphogenetic Proteins

Share to Disease Progression

Share to Esophageal Neoplasms

Share to Neoplasm Proteins

Share to Precancerous Conditions

Share to T-Box Domain Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 26783083
DOI: 10.1002/cam4.641
PMCID: PMC4864818

Genes

GDF7
TBX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Barrett-associated variants at GDF7 and TBX5 also increase esophageal adenocarcinoma risk.PMID 26783083Read ↗

Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus.Semantic proximity Read ↗

Common Variants Confer Susceptibility to Barrett's Esophagus: Insights from the First Genome-Wide Association Studies.Semantic proximity Read ↗

Overview of major molecular alterations during progression from Barrett's esophagus to esophageal adenocarcinomaSemantic proximity Read ↗

A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.Semantic proximity Read ↗

Germline genetic contributions to risk for esophageal adenocarcinoma, Barrett's esophagus, and gastroesophageal reflux.Semantic proximity Read ↗

Sex-Specific Genetic Associations for Barrett's Esophagus and Esophageal Adenocarcinoma.Semantic proximity Read ↗

Single nucleotide polymorphisms of caudal type homeobox 1 and 2 are associated with Barrett's esophagus.Semantic proximity Read ↗

Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis.Semantic proximity Read ↗

Identification of loci of functional relevance to Barrett's esophagus and esophageal adenocarcinoma: Cross-referencing of expression quantitative trait loci data from disease-relevant tissues with genetic association data.Semantic proximity Read ↗

Determining Risk of Barrett's Esophagus and Esophageal Adenocarcinoma Based on Epidemiologic Factors and Genetic Variants.Semantic proximity Read ↗

The Genetics of Barrett's Esophagus: A Familial and Population-Based Perspective.Semantic proximity Read ↗

Barrett's oesophagus: an ideal model to study cancer genetics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.