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Article

Overview of major molecular alterations during progression from Barrett's esophagus to esophageal adenocarcinoma

14 Jul 2016

Abstract excerpt

Esophageal adenocarcinoma (EAC) develops in the sequential transformation of normal epithelium into metaplastic epithelium, called Barrett's esophagus (BE), then to dysplasia, and finally cancer. BE is a common condition in which normal stratified squamous epithelium of the esophagus is replaced with an intestine-like columnar epithelium, and it is the most prominent risk factor for EAC. This review aims to...

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PMID: 27415609
DOI: 10.1111/nyas.13134

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