Article
Association of Tumor Necrosis Factor Receptor 1 Promoter Gene Polymorphisms (-580 A/G and -609 G/T) and TNFR1 Serum Levels with the Susceptibility to Gastric Precancerous Lesions and Gastric Cancer Related to H. pylori Infection in a Moroccan Population.
BioMed research international - 1 Jan 2020
Bounder Ghizlane, Jouimyi Mohamed R, Boura Hasna, Jouhadi Hassan, Badre Wafaa, Benomar Hakima, Kettani Anass, Lebrazi Halima, Maachi Fatima
Abstract excerpt
Chronic inflammation due to H. pylori infection is the risk factor of gastric cancer (GC). Through its receptor (TNFR1), TNF-α plays a fundamental role in inflammatory, infectious, and tumor processes. Dysregulation of TNFR1 gene expression could impact many biological processes that can lead to cancer. This study is aimed at evaluating the association of TNFR1 promoter gene polymorphisms (-580 A/G and -609 G/T)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.