Article
T-251A polymorphism of IL-8 relating to the development of histological gastritis and G-308A polymorphism of TNF-alpha relating to the development of macroscopic erosion.
European journal of gastroenterology & hepatology - 1 Mar 2008
Szoke Dominika, Molnar Bela, Solymosi Norbert, Klausz Gergely, Gyulai Zsofia, Toth Bernadett, Mandi Yvette, Tulassay Zsolt
Abstract excerpt
OBJECTIVES: Genetic variations of the inflammatory IL-8 and TNF-alpha genes can influence the outcome of gastric alterations. Our aims were to determine the prevalence and effect of the T-251A functional polymorphism of IL-8 and the G-308A polymorphism of TNF-alpha in histological and macroscopic gastric diseases related to Helicobacter pylori infection. METHODS: Genomic DNA was extracted from biopsy samples from...
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