Associations of the -238(G/A) and -308(G/A) TNF-α Promoter Polymorphisms and TNF-α Serum Levels with the Susceptibility to Gastric Precancerous Lesions and Gastric Cancer Related to Helicobacter pylori Infection in a Moroccan Population.

doi:10.31557/APJCP.2020.21.6.1623

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Associations of the -238(G/A) and -308(G/A) TNF-α Promoter Polymorphisms and TNF-α Serum Levels with the Susceptibility to Gastric Precancerous Lesions and Gastric Cancer Related to Helicobacter pylori Infection in a Moroccan Population.

Asian Pacific journal of cancer prevention : APJCP - 1 Jun 2020

Bounder Ghizlane, Jouimyi Mohamed Reda, Boura Hasna, Touati Eliette, Michel Valerie, Badre Wafaa, Jouhadi Hassan, Kadi Maria, Eljihad Meriem, Benomar Hakima, Kettani Anass, Lebrazi Halima, Maachi Fatima

Abstract excerpt

OBJECTIVE: Helicobacter pylori (H. pylori) induces the production of tumor necrosis factor-alpha (TNF-α), which is closely related to a gastric epithelial injury. TNF-α gene polymorphism and TNF-α serum levels are associated with various malignant conditions. Identification of the ideal marker for gastric cancer (GC) is still the leading aim of several trials. Physio-pathological considerations of GC led us to...

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PMID: 32592356
DOI: 10.31557/APJCP.2020.21.6.1623
PMCID: PMC7568906

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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