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Article

Functional properties of flagellin as a stimulator of innate immunity.

Scientific reports - 12 Jan 2016

Lu Yuan, Swartz James R

Abstract excerpt

We report the development of a well-defined flagellin-based nanoparticle stimulator and also provide a new mechanism of action model explaining how flagellin-triggered innate immunity has evolved to favor localized rather than potentially debilitating systemic immune stimulation. Cell-free protein synthesis (CFPS) was used to facilitate mutational analysis and precisely orientated display of flagellin on...

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Share to Flagellin
Share to Immunity, Innate
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Conformation

Share to Protein Interaction Domains and Motifs

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Share to Toll-Like Receptor 5

Source

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Identifiers

PMID: 26755208
DOI: 10.1038/srep18379
PMCID: PMC4709591

Genes

TLR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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