Article
Role of Lung Function Genes in the Development of Asthma.
PloS one - 1 Jan 2016
Yamada Hideyasu, Masuko Hironori, Yatagai Yohei, Sakamoto Tohru, Kaneko Yoshiko, Iijima Hiroaki, Naito Takashi, Noguchi Emiko, Konno Satoshi, Nishimura Masaharu, Hirota Tomomitsu, Tamari Mayumi, Hizawa Nobuyuki
Abstract excerpt
Although our previous GWAS failed to identify SNPs associated with pulmonary function at the level of genomewide significance, it did show that the heritability for FEV1/FVC was 41.6% in a Japanese population, suggesting that the heritability of pulmonary function traits can be explained by the additive effects of multiple common SNPs. In addition, our previous study indicated that pulmonary function genes...
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