Article
Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator.
Communications biology - 15 Nov 2021
Yamada Mitsuhiro, Motoike Ikuko N, Kojima Kaname, Fuse Nobuo, Hozawa Atsushi, Kuriyama Shinichi, Katsuoka Fumiki, Tadaka Shu, Shirota Matsuyuki, Sakurai Miyuki, Nakamura Tomohiro, Hamanaka Yohei, Suzuki Kichiya, Sugawara Junichi, Ogishima Soichi, Uruno Akira, Kodama Eiichi N, Fujino Naoya, Numakura Tadahisa, Ichikawa Tomohiro, Mitsune Ayumi, Ohe Takashi, Kinoshita Kengo, Ichinose Masakazu, Sugiura Hisatoshi, Yamamoto Masayuki
Abstract excerpt
Lung function reflects the ability of the respiratory system and is utilized for the assessment of respiratory diseases. Because type 2 airway inflammation influences lung function, genome wide association studies (GWAS) for lung function would be improved by adjustment with an indicator of the inflammation. Here, we performed a GWAS for lung function with adjustment for exhaled nitric oxide (FeNO) levels in two...
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