Article
Gene network analysis in a pediatric cohort identifies novel lung function genes.
PloS one - 1 Jan 2013
Ong Bruce A, Li Jin, McDonough Joseph M, Wei Zhi, Kim Cecilia, Chiavacci Rosetta, Mentch Frank, Caboot Jason B, Spergel Jonathan, Allen Julian L, Sleiman Patrick M A, Hakonarson Hakon
Abstract excerpt
Lung function is a heritable trait and serves as an important clinical predictor of morbidity and mortality for pulmonary conditions in adults, however, despite its importance, no studies have focused on uncovering pediatric-specific loci influencing lung function. To identify novel genetic determinants of pediatric lung function, we conducted a genome-wide association study (GWAS) of four pulmonary function...
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