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Article

Identification of a small molecule that simultaneously suppresses virulence and antibiotic resistance of Pseudomonas aeruginosa.

Scientific reports - 11 Jan 2016

Guo Qiaoyun, Wei Yu, Xia Bin, Jin Yongxin, Liu Chang, Pan Xiaolei, Shi Jing, Zhu Feng, Li Jinlong, Qian Lei, Liu Xinqi, Cheng Zhihui, Jin Shouguang, Lin Jianping, Wu Weihui

Abstract excerpt

The rising antibiotic resistance of bacteria imposes a severe threat on human health. Inhibition of bacterial virulence is an alternative approach to develop new antimicrobials. Molecules targeting antibiotic resistant enzymes have been used in combination with cognate antibiotics. It might be ideal that a molecule can simultaneously suppress virulence factors and antibiotic resistance. Here we combined genetic...

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Identifiers

PMID: 26751736
DOI: 10.1038/srep19141
PMCID: PMC4707474

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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