Article
A quorum sensing regulated small volatile molecule reduces acute virulence and promotes chronic infection phenotypes.
PLoS pathogens - 1 Aug 2011
Kesarwani Meenu, Hazan Ronen, He Jianxin, Que Yok-Ai, Que Yokai, Apidianakis Yiorgos, Lesic Biliana, Xiao Gaoping, Dekimpe Valérie, Milot Sylvain, Deziel Eric, Lépine François, Rahme Laurence G
Abstract excerpt
A significant number of environmental microorganisms can cause serious, even fatal, acute and chronic infections in humans. The severity and outcome of each type of infection depends on the expression of specific bacterial phenotypes controlled by complex regulatory networks that sense and respond to the host environment. Although bacterial signals that contribute to a successful acute infection have been...
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