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Article

Identification of genes involved in Pseudomonas aeruginosa biofilm-specific resistance to antibiotics.

PloS one - 1 Jan 2013

Zhang Li, Fritsch Meredith, Hammond Lisa, Landreville Ryan, Slatculescu Cristina, Colavita Antonio, Mah Thien-Fah

Abstract excerpt

Pseudomonas aeruginosa is a key opportunistic pathogen characterized by its biofilm formation ability and high-level multiple antibiotic resistance. By screening a library of random transposon insertion mutants with an increased biofilm-specifc antibiotic susceptibility, we previously identified 3 genes or operons of P. aeruginosa UCBPP-PA14 (ndvB, PA1875-1877 and tssC1) that do not affect biofilm formation but...

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Identifiers

PMID: 23637868
DOI: 10.1371/journal.pone.0061625
PMCID: PMC3634840

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