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Article

Retrospective case-control study of correlation between MTHFR gene and OSCC risk in North India.

Clinical oral investigations - 1 Jul 2017

Naqvi Hena, Ahmad Mohammad Kaleem, Hussain Syed Rizwan, Gupta Shalini, Waseem Mohammad, Mahdi Abbas Ali

Abstract excerpt

BACKGROUND: Oral squamous cell carcinoma (OSCC) occurrence appears to be the number one among all cancers in India. Folate is a methyl donor during DNA methylation, as it provides substrate for methylenetetrahydrofolate reductase (MTHFR) to convert 5,10-MTHF to 5-MTHF and subsequently metabolizes it to methionine. The purpose of this study was to identify MTHFR C677T gene polymorphism in patients with OSCC....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27774577
DOI: 10.1007/s00784-016-1976-z

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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