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Article

Influence of methylenetetrahydrofolate reductase polymorphisms in oral cancer patients.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Jan 2011

Sailasree R, Nalinakumari K R, Sebastian P, Kannan S

Abstract excerpt

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in folate metabolism. Two common polymorphisms associated with MTHFR gene - C677T and A1298C - influence the thermolabile nature and activity of the enzyme. This study aimed to investigate the role of MTHFR polymorphisms on oral cancer susceptibility and its potential impact on the prognostic outcome. METHODS: Oral cancer cases and controls...

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Source

Identifiers

PMID: 20923444
DOI: 10.1111/j.1600-0714.2010.00943.x

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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