Article
Global deletion of Panx3 produces multiple phenotypic effects in mouse humeri and femora.
Journal of anatomy - 1 May 2016
Caskenette Deidre, Penuela Silvia, Lee Vanessa, Barr Kevin, Beier Frank, Laird Dale W, Willmore Katherine E
Abstract excerpt
Pannexins form single-membrane channels that allow passage of small molecules between the intracellular and extracellular compartments. Of the three pannexin family members, Pannexin3 (Panx3) is the least studied but is highly expressed in skeletal tissues and is thought to play a role in the regulation of chondrocyte and osteoblast proliferation and differentiation. The purpose of our study is to closely examine...
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