Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human phosphatase CDC14A is recruited to the cell leading edge to regulate cell migration and adhesion

8 Jan 2016

Abstract excerpt

Cell adhesion and migration are highly dynamic biological processes that play important roles in organ development and cancer metastasis. Their tight regulation by small GTPases and protein phosphorylation make interrogation of these key processes of great importance. We now show that the conserved dual-specificity phosphatase human cell-division cycle 14A (hCDC14A) associates with the actin cytoskeleton of human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to Cellular Mechanics and Interactions
Share to Microtubule and mitosis dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26747605
DOI: 10.1073/pnas.1515605113

Provenance

PubMed metadata and Literature Corpus relationships.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human phosphatase CDC14A is recruited to the cell leading edge to regulate cell migration and adhesionPMID 26747605Read ↗

Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation.Semantic proximity Read ↗

Functional homology among human and fission yeast Cdc14 phosphatases.Semantic proximity Read ↗

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.Semantic proximity Read ↗

Phactr4 influences macrophage lamellipodial structure and dynamics through Arp2/3 complex and Ezrin regulationSemantic proximity Read ↗

Systematic functional genetic analysis of cell-substrate adhesionSemantic proximity Read ↗

HEF1-Aurora A Interactions: Points of Dialog between the Cell Cycle and Cell Attachment Signaling NetworksSemantic proximity Read ↗

The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers.Semantic proximity Read ↗

Folliculin Haploinsufficiency Causes Cellular Dysfunction of Pleural Mesothelial CellsSemantic proximity Read ↗

LINKIN-associated proteins necessary for tissue integrity during collective cell migrationSemantic proximity Read ↗

Coordination of NDC80 and Ska complexes at the kinetochore-microtubule interface in human cellsSemantic proximity Read ↗

Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription.Semantic proximity Read ↗

EYA4 drives breast cancer progression and metastasis through its novel role in replication stress avoidance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.