Article
The IL-33 gene is related to increased susceptibility to systemic sclerosis.
Rheumatology international - 1 Apr 2016
Koca Suleyman Serdar, Pehlivan Yavuz, Kara Murat, Alibaz-Oner Fatma, Oztuzcu Serdar, Yilmaz Neslihan, Cetin Gozde Yildirim, Kisacik Bunyamin, Ozgen Metin, Pamuk Omer Nuri, Direskeneli Haner, Sayarlioglu Mehmet, Onat Ahmet Mesut
Abstract excerpt
Systemic sclerosis (SSc) is a chronic inflammatory disease characterized by widespread fibrosis of the skin and several visceral organs. The pro-fibrotic potential of interleukin (IL)-33 has been demonstrated by in both in vitro and in vivo settings; moreover, increased level of IL-33 has also been reported in patients with SSc. Therefore, the aim of the present study was to detect the potential association of...
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