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Exploring the Impact of IL-33 Gene Polymorphism (rs1929992) on Susceptibility to Chronic Spontaneous Urticaria and Its Association with Serum Interleukin-33 Levels.

International journal of molecular sciences - 22 Dec 2024

Dobrican-Băruța Carmen-Teodora, Deleanu Diana Mihaela, Iancu Mihaela, Muntean Ioana Adriana, Nedelea Irena, Bălan Radu-Gheorghe, Procopciuc Lucia Maria, Filip Gabriela Adriana

Abstract excerpt

Urticaria is a debilitating skin condition affecting up to 20% of the global population, characterized by erythematous, maculopapular lesions and significant quality of life impairment. This study focused on the role of interleukin 33 (IL-33) and its polymorphisms, particularly SNP rs1929992, in chronic spontaneous urticaria (CSU). Using demographic, clinical, and laboratory data from CSU patients and controls,...

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PMID: 39769469
DOI: 10.3390/ijms252413709

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