Article
Association of interleukin-1 family cytokines single nucleotide polymorphisms with susceptibility to systemic sclerosis: an independent case-control study and a meta-analysis.
Immunologic research - 1 Aug 2016
Huang Xiao-Lei, Wu Guo-Cui, Wang Yu-Jie, Yang Xiao-Ke, Yang Guo-Jun, Tao Jin-Hui, Duan Yu, Yan Jun-Wei, Li Xiang-Pei, Ye Dong-Qing, Wang Jing
Abstract excerpt
The aim of our study was to investigate the association of five single nucleotide polymorphisms in interleukin-1 (IL-1) gene with susceptibility to systemic sclerosis (SSc) in a Chinese population. A total of 58 SSc patients and 113 healthy controls were enrolled. TaqMan allele discrimination assay was performed to detect the genotyping of IL-1A -889C/T (rs1800587), IL-1B -511C/T (rs16944), IL-18 -607C/A...
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