Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IgG4 Characteristics and Functions in Cancer Immunity

1 Jan 2016

Abstract excerpt

IgG4 is the least abundant subclass of IgG in normal human serum, but elevated IgG4 levels are triggered in response to a chronic antigenic stimulus and inflammation. Since the immune system is exposed to tumor-associated antigens over a relatively long period of time, and tumors notoriously promote inflammation, it is unsurprising that IgG4 has been implicated in certain tumor types. Despite differing from other...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glycosylation and Glycoproteins Research
Share to Monoclonal and Polyclonal Antibodies Research
Share to Neuroendocrine Tumor Research Advances

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26742760
DOI: 10.1007/s11882-015-0580-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IgG4 Characteristics and Functions in Cancer ImmunityPMID 26742760Read ↗

Role of IgG4 Antibodies in Human Health and DiseaseSemantic proximity Read ↗

IgG4 ‐Related Disease: Emerging Roles of Novel Genetic Variants, Immune Cell Subsets and Therapeutic TargetsSemantic proximity Read ↗

IgG4-related disease: an update on pathophysiology and implications for clinical careSemantic proximity Read ↗

Immune dysregulation in immunoglobulin G4–related diseaseSemantic proximity Read ↗

Advances in the diagnosis and management of IgG4 related disease.Semantic proximity Read ↗

Spatial and phenotypic plasticity of B cells in remodeling the tumor microenvironment.Semantic proximity Read ↗

New insights into IgG4-related disease: emerging new CD4+ T-cell subsetsSemantic proximity Read ↗

Immune phenotype changes in IgG4-related disease: CD161 + Treg and Foxp3 + Treg.Semantic proximity Read ↗

Immunoglobulin Expression in Cancer Cells and Its Critical Roles in TumorigenesisSemantic proximity Read ↗

Revealing the role of regulatory b cells in cancer: development, function and treatment significanceSemantic proximity Read ↗

Distinct transcriptional programs define human IgG4 <sup>+</sup> memory B cellsSemantic proximity Read ↗

A germline variant of human IgG1+ B cell receptor represses colorectal tumorigenesis and progression by shaping the tumor microenvironmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.