Article
Immune phenotype changes in IgG4-related disease: CD161 + Treg and Foxp3 + Treg.
Clinical rheumatology - 1 Apr 2023
Bian Wenjie, Li Yingni, Sun Feng, Sun Xiaolin, Li Ru, Xia Changsheng, Fu Jiangnan, Zhang Yuxin, Chen Shuang, Liu Yanying
Abstract excerpt
OBJECTIVE: We aimed to characterize the alterations in the immune phenotypes and explore the potential relevance to pathogenesis in IgG4-RD. METHODS: Forty-two IgG4-RD patients and thirty-eight healthy controls were recruited in this study. Peripheral immunocompetent cells including T cells, CD4 + T cells, CD8 + T cells, B cells, NK cells CD4 + CD45RA + T cells (naïve T cells), CD4 + CD25 - / + Foxp3 - T cells...
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