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Article

Immune dysregulation in immunoglobulin G4–related disease

9 Jan 2023

Abstract excerpt

(IgG4-RD) is an immune-mediated fibrotic disorder characterized by severe resolution of inflammation and dysregulation of wound healing. IgG4-RD has been considered a unique disease since 2003, and significant progress has been achieved in the understanding of its essential features. The central role of B cells in IgG4-RD has been demonstrated by the robust clinical responsiveness of IgG4-RD to B cell depletion...

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PMID: 36654676
DOI: 10.1016/j.jdsr.2022.12.002

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