Frequencies of an IFNL4 Variant in an Admixed Population from Amazonia and Its Influence on Hepatitis C Infection.

doi:10.3390/ijms252312764

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Article

Frequencies of an IFNL4 Variant in an Admixed Population from Amazonia and Its Influence on Hepatitis C Infection.

International journal of molecular sciences - 27 Nov 2024

Angelim Carolina Cabral, Andrade Álesson Adam Fonseca, de Sousa Renata Santos, Correa Raissa Lima, Sacramento Amanda Roberta Vieira, Martins Letícia Dias, Conde Simone Regina Souza da Silva, Vallinoto Antonio Carlos Rosário, Feitosa Rosimar Neris Martins, Costa Greice de Lemos Cardoso

Abstract excerpt

The rs12979860 polymorphism, related to the IFNL4 gene, is suggested as a factor that impacts fibrosis progression in hepatitis C virus (HCV) infection and exhibits a wide distribution pattern across global populations. In this retrospective cross-sectional study, we aimed to investigate the frequency of this variant in an Amazonian population from Brazil, as well as its association with liver fibrosis...

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PMID: 39684474
DOI: 10.3390/ijms252312764
PMCID: PMC11640799

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