Article
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus.
Nature - 8 Oct 2009
Thomas David L, Thio Chloe L, Martin Maureen P, Qi Ying, Ge Dongliang, O'Huigin Colm, Kidd Judith, Kidd Kenneth, Khakoo Salim I, Alexander Graeme, Goedert James J, Kirk Gregory D, Donfield Sharyne M, Rosen Hugo R, Tobler Leslie H, Busch Michael P, McHutchison John G, Goldstein David B, Carrington Mary
Abstract excerpt
Hepatitis C virus (HCV) infection is the most common blood-borne infection in the United States, with estimates of 4 million HCV-infected individuals in the United States and 170 million worldwide. Most (70-80%) HCV infections persist and about 30% of individuals with persistent infection develop chronic liver disease, including cirrhosis and hepatocellular carcinoma. Epidemiological, viral and host factors have...
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