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Article

Common TLR1 genetic variation is not associated with death from melioidosis, a common cause of sepsis in rural Thailand.

PloS one - 1 Jan 2014

Chantratita Narisara, Tandhavanant Sarunporn, Myers Nicolle D, Chierakul Wirongrong, Wuthiekanun Vanaporn, Mahavanakul Weera, Limmathurotsakul Direk, Peacock Sharon J, West T Eoin

Abstract excerpt

Melioidosis, infection caused by the Gram-negative bacterium Burkholderia pseudomallei, is a common cause of sepsis in northeast Thailand. In white North Americans, common functional genetic variation in TLR1 is associated with organ failure and death from sepsis. We hypothesized that TLR1 variants would be associated with outcomes in Thais with melioidosis. We collated the global frequencies of three TLR1...

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Identifiers

PMID: 24392083
DOI: 10.1371/journal.pone.0083285
PMCID: PMC3879377

Genes

TLR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Common TLR1 genetic variation is not associated with death from melioidosis, a common cause of sepsis in rural Thailand.PMID 24392083Read ↗

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