Article
Identification of imprinting regulators at the Meg3 differentially methylated region.
Genomics - 1 Sept 2012
McMurray Erin N, Schmidt Jennifer V
Abstract excerpt
Genomic imprinting at the Delta-like 1 (Dlk1)-Maternally expressed gene 3 (Meg3) locus is regulated by the Meg3 differentially methylated region (DMR), but the mechanism by which this DMR acts is unknown. The goal of this study was to analyze the Meg3 DMR during imprinting establishment and maintenance for the presence of histone modifications and trans-acting DNA binding proteins using chromatin...
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