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Article

Roles of Interferon Regulatory Factors in Chronic Myeloid Leukemia

5 Jan 2016

Abstract excerpt

The Interferon Regulatory Factor (IRF) family consists of multiple transcription factors involved in the regulation of a variety of biological processes. Originally identified as transcriptional regulators of the type I interferon system, IRFs play a pivotal role in adaptive immunity, cell growth, differentiation and tumorigenesis. Hence, understanding IRF biology has important implications in the host response...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26728039
DOI: 10.2174/1568009616666160105105857

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