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Article

Interferon regulatory factor 1 inactivation in human cancer

29 Mar 2018

Abstract excerpt

Interferon regulatory factors (IRFs) are a group of closely related proteins collectively referred to as the IRF family. Members of this family were originally recognized for their roles in inflammatory responses; however, recent research has suggested that they are also involved in tumor biology. This review focusses on current knowledge of the roles of IRF-1 and IRF-2 in human cancer, with particular attention...

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PMID: 29599126
DOI: 10.1042/bsr20171672

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