Article
Focus on Kir6.2: a key component of the ATP-sensitive potassium channel.
Journal of molecular and cellular cardiology - 1 Jun 2005
Haider Shozeb, Antcliff Jennifer F, Proks Peter, Sansom Mark S P, Ashcroft Frances M
Abstract excerpt
ATP-sensitive potassium (K(ATP)) channels are found in a wide variety of cell types where they couple cell metabolism to electrical activity. In glucose-sensing tissues, these channels respond to fluctuating changes in blood glucose concentration, but in other tissues they are activated only under ischemic conditions or in response to hormonal stimulation. Although K(ATP) channels in different tissues have...
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