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Article

WT1 mutation in pediatric patients with acute myeloid leukemia: a report from the Japanese Childhood AML Cooperative Study Group.

International journal of hematology - 1 Oct 2013

Sano Hirozumi, Shimada Akira, Tabuchi Ken, Taki Tomohiko, Murata Chisato, Park Myoung-ja, Ohki Kentaro, Sotomatsu Manabu, Adachi Souichi, Tawa Akio, Kobayashi Ryoji, Horibe Keizo, Tsuchida Masahiro, Hanada Ryoji, Tsukimoto Ichiro, Hayashi Yasuhide

Abstract excerpt

Mutations in Wilms tumor 1 (WT1) have been reported in 10-22 % of patients with cytogenetically normal acute myeloid leukemia (CN-AML), but the prognostic implications of these abnormalities have not been clarified in either adults or children. One hundred and fifty-seven pediatric AML patients were analyzed for WT1 mutations around hotspots at exons 7 and 9; however, amplification of the WT1 gene by the reverse...

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Share to Chromosome Banding
Share to Infant, Newborn

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Myeloid, Acute

Share to Patient Outcome Assessment

Share to Proportional Hazards Models

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Source

Identifiers

PMID: 23979985
DOI: 10.1007/s12185-013-1409-6

Genes

FLT3
KIT
KRAS
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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