Article
Risk-Reducing Genetic Variant of Wilms Tumor 1 Gene rs16754 in Korean Patients With BCR-ABL1-Negative Myeloproliferative Neoplasm.
Annals of laboratory medicine - 1 May 2015
Kim Namhee, Kim In-Suk, Chang Chulhun L, Kang Jeong-Eun, Lee Eun Yup, Shin Ho-Jin
Abstract excerpt
The genetic variant rs16754 of Wilms tumor gene 1 (WT1) has recently been described as an independent prognostic factor in AML patients. It is of great interest to test whether WT1 single nucleotide polymorphism can be used as a molecular marker in other types of cancer, to improve risk and treatment stratification. We performed sequencing analysis of exons 7 and 9 of WT1, which are known mutational hotspots, in...
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