Article

Wilms Tumor 1 Mutations are Independent Poor Prognostic Factors in Pediatric Acute Myeloid Leukemia

2020-10-26

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>The role of <italic>Wilms tumor 1</italic><bold> (</bold><italic>WT1</italic>) mutations remains controversial for patients with acute myeloid leukemia (AML) with regard to the prognostic impact. Here, we aimed to determine the clinical implication of <italic>WT1</italic> mutations in a large cohort of pediatric AML. <bold>Methods: </bold>The clinical data of 87...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b2f46200-c240-5f78-8d67-7eaca0d6b84f
DOI: 10.21203/rs.3.rs-95114/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Wilms Tumor 1 Mutations are Independent Poor Prognostic Factors in Pediatric Acute Myeloid LeukemiaDOI 10.21203/rs.3.rs-95114/v1Read

Clinical relevance of Wilms tumor 1 gene mutations in childhood acute myeloid leukemia.Semantic proximity Read

Expression of Wilms’ Tumor Gene 1 and Its Clinical Significance in Children with Acute Lymphocytic LeukemiaSemantic proximity Read

Prevalence and prognostic implications of WT1 mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology Group.Semantic proximity Read

Frequency and Clinical Impact of WT1 Mutations in the Context of CEBPA-Mutated Acute Myeloid LeukemiaSemantic proximity Read

Prognostic impact of Wilms tumor gene mutations in Egyptian patients with acute myeloid leukemia with normal karyotype.Semantic proximity Read

Prevalence and Prognostic Impact of Wilms' Tumor 1 (WT1) Gene, Including SNP rs16754 in Cytogenetically Normal Acute Myeloblastic Leukemia (CN-AML): An Iranian Experience.Semantic proximity Read

Prognostic Impact of Wilms' Tumour 1 Mutation in Patients with Acute Myeloid Leukaemia.Semantic proximity Read

Friend or foe? The case of Wilms' Tumor 1 (WT1) mutations in acute myeloid leukemia.Semantic proximity Read

The clinical relevance of Wilms Tumour 1 (WT1) gene mutations in acute leukaemia.Semantic proximity Read

Wilms' tumor gene 1 in hematological malignancies: friend or foe?Semantic proximity Read

WT1 mutations are secondary events in AML, show varying frequencies and impact on prognosis between genetic subgroups.Semantic proximity Read

Impact of Wilms' tumor 1 gene (WT1) mutation on outcome of allogeneic hematopoietic-cell transplantation for acute myeloid leukemia: a retrospective multicenter cohort study from the ALWP/EBMT registry.Semantic proximity Read